The full-back, who last played against Derby in October, is likely to be ruled out for several more months.
"We’ve had news that the best we can hope for with David Murphy will be late February or early March," confirmed a disappointed Lee Clark.
"We’re really down to the bare-bones in terms of defenders, hence the reason why it was necessary to call Amari’i Bell and Will Packwood back.
"We’ve also got a couple of players on the fringe of suspension with the accumulation of yellow cards. And with the number of games coming up in a short period of time it was imperative I got them in."
The news regarding Mitch Hancox is a little more positive. The young full-back was forced to come off with a knee injury towards the end of Blues' last outing against Middlesbrough.
"Mitch took quite a serious smash to the knee with the ferocity of the tackle," said Clark. "He won’t be with us until the New Year. But hopefully it won’t be too long into the New Year, possibly even the New Year’s Day game at a push (against Barnsley).
"He doesn’t go down for nothing, and then when he tried to play on and within seconds flagged it up I thought there was some sort of situation.
"There are some strains to certain ligaments, but thankfully they are nice and stable and we’re not down the Matt Green or Neal Eardley route. He'll just need rest and rehab."
The Blues boss also revealed that he would be without the services of Lee Novak for Saturday's trip to Bournemouth, after the forward injured his leg earlier this week.
He added: "We’ll be without Lee Novak on Saturday. He took a nasty hit to his leg.
"He’s had an X-ray and a scan to see if there was any fracture, but thankfully that’s not the case. He has an outside chance of being ready for Forest."
Elsewhere in the squad, Matt Green (knee), Jonathan Spector (thigh), Akwasi Asante (hamstring) and Neal Eardley (knee) are all still out.