The Americans will attend a training camp in the German city of Frankfurt before travelling to Cyprus to face Ukraine. The friendly fixture was moved to Antonis Papadopoulos Stadium in Larnaca from its original venue of Kharkiv due to the current conditions in Ukraine.
It is Boston-born Packwood's first call up to Jurgen Klinsmann's US roster having represented his homeland at U17, U18 and U20 levels.
Shortly after announcing his 24-man squad, Klinsmann said: "Having this Ukraine game is a huge opportunity, mainly for our European-based players. You want to give them a chance to show where they are at and what’s going on in their specific situation. It’s great to call in players like Oguchi Onyewu, Will Packwood – his first time to come in – Tim Ream, who is playing consistently well at Bolton, Danny Williams, who has now kind of made his way through at Reading and playing week-in, week-out, and Juan Agudelo, who is now in Holland.
“It’s a huge opportunity for all those guys to prove to us that they are eager and hungry to jump on the train to the World Cup. We will get a good picture of them over those couple of days, and therefore, we left almost all the MLS players back in the United States.”