It will be the first time he has refereed a Blues game.BCFC
So far this season, the Greater Manchester-based official has refereed six games where he has produced a total of 27 yellow cards, but no reds.
It will be the first time he has refereed a Blues game.
The last Charlton game he took charge of was their 2-2 Championship draw at Barnsley in August.
Seven players were booked in that game; including Adedeji Oshilaja, Josh Cullen and Chuks Aneke for The Addicks.
He has refereed two Charlton games in total - one of which they won and one they drew.
Mr Donohue will be assisted on Saturday by Adrian Waters and Ian Cooper, with Matt Foley acting as the fourth official.